Relation of Chronic Lead Poisoning and Oxidant / Antioxidant State: Experimental Toxicology

The administration of antioxidants (ascorbic acid, ?- tocopherol, N-acetylcysteine and L-methionine) should be mandatory in workers before exposure to lead. - Individuals should take supplements with antioxidants in amounts that are of recommended dietary allowance values. As safety guidance, tolerable upper intake levels have been established by the Food and Nutrition Board, Institute of Medicine, at 1000 mg for ?- tocopherol (vitamin E) and 2000 mg for ascorbic acid (vitamin C) in adults. - Advise caregivers to provide adequate intake of vitamin C. For children about the age of 6 months and older, they should be provided twice daily with food rich in vitamin C preferably with meals, as a way of improving their iron absorption.